In the current report an inventory is made of chemicals that may require extra policy attention. The focus is on chemicals that are of relevance for the Netherlands, and that have not been the subject or are not planned to be the subject of (inter)national risk assessment programmes. Chemicals that are encountered and identified during analytical-chemical surveys are listed. As a second category groups of potentially hazardous chemicals that are frequently mentioned in recent literature are discussed. Finally, information from the Dutch registration on emission of substances is used to identify substances of possible concern.